(Note: Image from online resources)

Microscopic technology, as a core tool for scientific discovery, medical research and industrial innovation, is of great significance in the following aspects: breaking through the limits of human perception, revealing the microscopic world invisible to the naked eye, and promoting the progress of basic science; Solving problems in the minute details, failure analysis from the cellular fluoroscopy required for disease diagnosis to material surface features, and providing detailed and comprehensive evidence; The continuous innovation of driving technology, with cutting-edge fields such as gene editing, nanotechnology, and semiconductor chips all relying on the support of microscopic technology.

(Note: Image from online resources)

Super-Resolution Microscopy (SRM) is a significant breakthrough in the field of optical microscopy in recent years. It has broken through the diffraction limit of traditional optical microscopy, enabling higher resolution and the observation of smaller structures, such as: In the field of biomedicine, super-resolution microscopic imaging technology is generally used to observe biological samples with resolutions far exceeding those of traditional optical microscopes. By using special fluorescence labeling, pulse excitation or image localization algorithms, its resolution can reach the nanometer level, thereby revealing the internal structure and dynamic process details of cells.

(Note: Image from online resources)

When using traditional microscopes for live cell imaging, it is often interfered by non-focal plane blurring signals and background signals, resulting in a decrease in image contrast and resolution. The super-resolution microscope uses structured light illumination, which can perform optical section imaging on large-volume samples and has clear contrast and high resolution in all dimensions. While providing illumination, it is necessary to quickly capture the fluorescence signals from different focal planes and then merge them into a clear image. At this point, the rapid response and precise positioning capabilities of the piezoelectric objective lens locator are relied upon.  

(Note: Image from online resources)

The core requirements of super-resolution imaging are nanoscale precision and ultra-fast response speed. It must not only be capable of stably controlling the precise movement of the objective lens at the nanoscale but also be able to track the dynamic changes of fluorescent molecules in real time. In the precise optical system of a super-resolution microscope, the piezoelectric objective scanner can be said to be an irreplaceable key component. This precision positioning device based on piezoelectric ceramic technology needs to minimize vibration, provide the Z-direction focusing accuracy and stability required for super-resolution imaging, and help super-resolution microscopes achieve nanometer-level precision.

Characteristics

• Travel to 100μm

• Load capacity to 0.4kg

• Millisecond response time

• Closed loop for high repeatability

• Open-loop and closed-loop options are available

Typical Model

P76 series piezoelectric objective scanner features a large load capacity up to 900g, Z-axis linear motion range from 40 to 200μm, adopting flexible hinge mechanism, no friction, good linearity, high closed-loop positioning accuracy.The detachable threaded adapter design makes it compatible with various models of microscopes.

Characteristics

• Travel to 200μm

• Load capacity to 900g

• Millisecond response time

• Closed loop for high repeatability

• Excellent focusing stability

Typical Model

P79 is a 1-3 axes micro-motion platform, mainly used for supporting macro-motion XY-axes micro-scanning stages. After the macro-motion XY-axes positions the sample, P79 platform can perform fast Z-axis focus adjustments with milliseconds step time.

Characteristics

• 50 to 200μm travel for choice

• Large aperture

• Z or XYZ version

• Load capacity to 2kg  

• High closed-loop repeatability

• UHV version available

Typical Model

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