ince the cost of high-precision microscopy equipment is usually very high, the choice of microscopy equipment is generally at the micrometer accuracy, thereby controlling the purchase cost. Moreover, the observation accuracy and observation range of such microscopic equipment are determined before shipped. When higher-precision observation or larger-range observation is required, the corresponding requirements cannot be met.

CoreMorrow could provide the piezo objective scanner and high-precision XY-axis motorized stage and corresponding control systems to solve the problems of low precision and small observation range of existing microscope systems for customers.

The system could improve the precision of the microscopic imaging system by thousands of times, and could be more suitable for monitoring and imaging of ultra-small structures such as small cells.

Components and functions

The solution consists of piezoelectric objective scanner, high-precision XY-axis motorized stage and corresponding controller. The function of the piezoelectric objective scanner is to perform rapid focus adjustment in the Z direction, and its resolution can reach nanometers. The function of high-precision two-dimensional motorized stage is to increase the adjustment range of the sample in the XY direction, up to one hundred millimeters.

Piezo Objective Scanner

The piezoelectric objective scanner is connected to the lens through a thread adapter, and the thread can be arbitrarily selected. It can be adapted to a variety of standard lenses such as Olympus Olympus, Zeiss Zeiss, Nikon Nikon, Leica Leica, and can be customized.

The optional travel range of piezo objective scanner is 75μm, 100μm, 200μm, 500μm, 1000μm, etc., the resolution can be as high as 2.5nm, and the load ranges from 0.2kg to 1.5kg. It is driven by piezoelectric, and the response speed is up to 5ms, which meets the requirements of fast focusing.The built-in sensor can be selected to make it have high linearity and repeatability.

XY-axis Motorized Stage

The high-precision XY-axis motorized stage is driven by linear/servo motor. The stroke can reach 150mm×100mm, the adjustment speed can reach 300mm/s, and acceleration can reach 1000mm/s², the resolution can reach 0.1μm, and the load can reach 3kg. It is made of industrial-grade flame-retardant shell, precision-processed aluminum alloy substrate, high-precision ball guide rail and other materials. Optional built-in high-precision sensor for closed-loop micron-level positioning control. And also could be controlled by software and handle.

In addition, CoreMorrow XY piezoelectric nanopositioning stage can also be selected to provide higher scanning accuracy.

Application

The following figure shows the P72 series piezoelectric objective scanner mounted on common biological microscope to improve the resolution and accuracy of imaging.